Prevagen Review: Ingredients, Side Effects, Cost, and More (2024)

Prevagen is a dietary supplement that helps improve memory, learning and focus. The product was developed by neuroscientist David Perlmutter to help prevent the onset of age-related cognitive decline in people over 40 years old. To be used as directed with medical supervision for best results.

The “what is the primary ingredient in prevagen” is a question that many people have been asking. The answer to this question is, “Prevagen contains no artificial ingredients or fillers and is made with only natural ingredients.”

Prevagen Review: Ingredients, Side Effects, Cost, and More (1)


  • Return/refund policy of 45 days
  • Vitamin D insufficiency is a typical occurrence.
  • Major shops carry it.


  • There isn’t enough proof to back such allegations.
  • There are no independent third-party safety and purity tests.
  • Expensive

What Exactly Is Prevagen?

Prevagen is a nutritional supplement that promotes brain health.

Prevagen comes in a variety of forms, but all of them include the same two active ingredients: Apoaequorin and vitamin D.

Prevagen’s products are distinguished by the quantity of Apoaequorin they contain. Apoaequorin has been linked to improved memory in senior citizens.

Users will have a Mind that is sharper and Greater clarity of thought, according to the product, which has been scientifically proved to assist relieve indicators associated to minor memory loss that happens with age.

The brain is the body’s command center, yet most people are unaware of its many activities since we aren’t aware of much brain activity outside of core thoughts, sensations, and moods.

Prevagen’s main constituent is said to help with cognitive function and age-related memory decline.

While it’s true that aging has an influence on brain health, several lifestyle variables play a part in maintaining brain function as you age.

Diet, sleep, physical exercise, and stress levels may all have an impact on your brain’s health.

Anything that causes inflammation and oxidative stress accelerates aging in general.

As a certified dietitian, it is my responsibility to inform you that no supplement will compensate for or eliminate the inflammatory consequences of a poor diet, smoking, excessive alcohol use, poor sleep, or a lack of physical exercise.

Ingredients Evaluation

There are just two active components in Prevagen: Apoaequorin and vitamin D:


Apoaequorin is a calcium-binding protein identified in a Pacific Ocean type of bioluminescent jellyfish.

Regular vigour Prevagen includes 10 mg of apoaequorin, with 20 mg and 40 mg in the additional strength and professional strength versions, respectively.

Consumers are regularly told by Prevagen’s marketing how unique and scientifically proved safe this chemical is.

I’m not sure how someone came up with the idea of a link between a material found in one type of jellyfish drifting about in the ocean and the human brain, but let’s look at the facts.

This substance, according to the product, has been scientifically proved to aid memory and promote brain function by controlling calcium levels in brain cells.

Calcium is required for memory and the creation of neurotransmitters.

I went to Prevagen’s website and looked at the “science” page, where they mention various studies to back up their claims of safety and effectiveness.

High dosages of apoaequorin were tried on lab rats in the experiments referenced on Prevagen’s website.

They declared the component acceptable for human consumption since the doses given to the rats were thousands of times larger than the quantity in Prevagen.

They also reference a single research that employed simulated digestion to see whether apoaequorin is degraded by pepsin, the stomach’s major digesting enzyme, and hence unlikely to produce an allergic response in people.

Because this substance gets broken down in the stomach, I’m not sure how it can get to the brain to be of any use. This conclusion was reached without the use of human subjects.

In terms of effectiveness, the Madison Memory Study, which was undertaken by the developers of Prevagen and is an instant red flag in my view, is the only clinical data available.

Prevagen often refers to this double-blind placebo-controlled experiment to emphasize that apoaequorin has been clinically evaluated and proved to be beneficial.

The wording seems to be scientific and reliable, however there are a few flaws.

A total of 218 persons between the ages of 40 and 91 with self-reported memory difficulties took part in the research.

Individuals who took Prevagen for 90 days compared to placebo exhibited substantial improvements in verbal learning, working memory, and memory recall, according to computer testing.

These studies are vulnerable to bias since they were done internally by the producers of Prevagen. They should be taken with a grain of salt.

There have been no clinical tests or imaging studies to show that eating apoaequorin raises the quantity of calcium in brain cells or enhances brain activity.

There were no further trials on this substance, according to a deeper look into the data.

What’s Final Thoughts?

There have been no human studies on the safety of apoaequorin, and the claims that it may boost cognitive function and memory are just that: lofty promises without enough proof to back them up.


Apoaequorin is a jellyfish-specific protein. There are no studies that support the use of apoaequorin for brain health and memory, except from those undertaken by the developers of Prevagen.

Vitamin D3 is a nutrient that is found in

All formulations of Prevagen contain 50 micrograms (mcg) of Vitamin D3 is a nutrient that is found in per serving as cholecalciferol.

For people aged 19–70 years, the Recommended Dietary Allowance for vitamin D is 15 mcg per day, and for those aged 71 years and over, it is 20 mcg per day.

Vitamin D is important for brain health.

Evidence shows that sufficient vitamin D consumption may help maintain brain function as people age, and lack has been related to an increased risk of mental illnesses including depression, dementia, and autism.


Vitamin D3 is a nutrient that is found in is an essential nutrient with many roles, one of which is supportingbrain health.

Conclusion on Benefits Claimed

Based on the current studies, we’ve compiled a summary of the available evidence regarding Prevagen’s stated benefits:

Optimal brain functionEvidence of Moderate Strength
Mind that is sharperThere is no proof.
Greater clarity of thoughtThere is no proof.

Other than research conducted by the makers of Prevagen, there is There is no proof. to support the safety, dosage, or benefit of taking Apoaequorin for brain health and memory.

Vitamin D insufficiency has been related to a variety of mental illnesses, and supplementation may help to improve brain health and function.

However, there is There is no proof. that vitamin D supplementation will enhance memory or result in clearer and sharper thinking.

Safety, Dosage, and Side Effects

Prevagen comes in a one-tablet-per-day serving amount, regardless of the formula. Prevagen is best taken first thing in the morning, with or without food.

Despite the fact that Prevagen has been available for a long time, I am concerned about its long-term safety.

The producers of Prevagen performed the sole scientific research involving human intake, and they reported that it was well tolerated with no significant negative effects.

Some users have reported nausea, headaches, and dizziness as adverse effects. Due to a dearth of study, the long-term negative effects of using Prevagen remain unclear.

It’s worth mentioning that using Prevagen with another vitamin D supplement might result in an excess of vitamin D.

Each Prevagen dosage includes 50 micrograms of vitamin D. The maximum daily dosage of vitamin D that is unlikely to induce harmful effects is established at 100 micrograms.

Some prescription drugs, such as cholesterol-lowering statins, may be less effective if you take too much vitamin D.

If you’re thinking about trying Prevagen, make an appointment with a doctor beforehand.

Where to Buy and How Much

Prevagen is available through Amazon, Target, Walmart, Walgreens, and CVS, among other big retailers, grocery shops, and pharmacy stores.

Prevagen is available in three different formulations, but how can you know which one is best for you?

There are no suggested intakes for apoaequorin since it hasn’t been tested for human consumption.

Prevagen’s creators leave it up to the customer to determine how much is enough, and I’m guessing they’re betting that most purchasers would fall into the “more is better” mindset.

  • Regular vigour A 30-count bottle of Prevagen costs $40, whereas a 60-count bottle costs $75.
  • Extra-strength Prevagen is now available in 30 and 60 count sizes, with prices ranging from $60 to $110.
  • The professional capability A 30-day supply of Prevagen costs $90.

If you prefer not to swallow pills, the normal and extra-strength formulae are now available in chewable form for the same price as tablets.

Prevagen offers a 45-day return and refund policy on any of their goods if purchased from an authorized dealer and the original receipt and packaging are kept.

Their website has detailed return guidelines as well as a list of approved retail outlets.

Prevagen is available for purchase on Amazon.

How does Prevagen stack up against the competition?

There isn’t much to compare Prevagen to, particularly in terms of pricing, since it’s the only memory and brain health vitamin that includes apoaequorin.

Neuriva is another well-known and well-marketed brain supplement. Cherry coffee extract and phosphatidylserine are the active components.

Both chemicals have had more research done on them than apoaequorin, and there is significant evidence that they help with attention, memory, learning, accuracy, and concentration.

One thing to keep in mind regarding Neuriva is that it includes soy, which means it’s not ideal for anyone who have a soy allergy.

Neuriva is available in a number of different forms. Prevagen is more expensive than the original product, which costs $32.99 for a month’s supply.

What’s the Difference Between Prevagen and Neuriva?

Other evidence-backed active components included in other top-selling memory and brain health supplements include B vitamins, mushrooms, and herbal substances like Ginkgo biloba and Rhodiola rosea, according to an Amazon search.

DHA/EPA (omega-3 fatty acid) supplements are often advised for brain health, as previously indicated.

Nordic Naturals is a well-known omega-3 supplement brand. Nordic Naturals Ultimate Omega costs $32.49 on Amazon for a 45-day supply, or around 72 cents each day.


In comparison to Neuriva and omega-3 fatty acid supplements, Prevagen looks to be pricey and lacks proof to back its health claims.

Prevagen Frequently Asked Questions

  • What is the primary component of Prevagen?

    There are just two active components in Prevagen: apoaequorin and vitamin D. Apoaequorin is a jellyfish protein that is thought to aid memory by controlling calcium levels in the brain.

  • Is Prevagen effective for memory loss?

    While vitamin D insufficiency has been related to brain diseases, there are no studies that support the safety, dose, or effectiveness of taking apoaequorin for brain health and memory other than those undertaken by the developers of Prevagen.

  • What are the risks associated with using Prevagen?

    Other than those undertaken by the developers of Prevagen, there have been no studies on the safety of using apoaequorin.

    Some users have reported nausea, headaches, and dizziness as adverse effects. The long-term consequences of using Prevagen, if any, are unknown.

  • What is the monthly cost of Prevagen?

    The price is determined on the product strength you choose. Prevagen may cost anything from $40 to $90 for a month’s supply, or $1.33 to $3.00 each day.

  • Is Prevagen a good investment?

    Because no other memory/brain supplement includes apoaequorin, it’s difficult to compare.

    Prevagen looks to be pricey when compared to many other popular memory and brain health supplements that have no evidence to back up their claims, therefore I’d say no, Prevagen is not worth the money.

  • What is the maximum number of Prevagen pills I may take each day?

    1 pill per day is the recommended dose for all Prevagen formulations. Because there is a dearth of safety information on the active ingredient, apoaequorin, you should not take more than this dosage.

Final Thoughts

There isn’t enough data to back up claims that the active component in Prevagen, apoaequorin, may boost memory or promote brain function in any substantial manner.

Because this chemical has only been studied for safety in lab rats, its long-term safety is likewise in doubt.

Prevagen has been chastised by the Federal Drug Administration and the Federal Trade Commission for making claims that go beyond what is legal for a dietary supplement.

Prevagen also includes 250 percent of the RDA for Vitamin D for individuals over the age of 71.

Vitamin D supplementation may help the body and mind age gracefully, but you don’t need to take a Prevagen to receive your daily amount.

If you’re thinking about taking Prevagen, I’d suggest you to proceed with caution and consult with a physician first.

Our Dietitian’s Remarks

Many lifestyle factors play a role in supporting brain function as you get older. Diet, sleep, physical exercise, and stress levels may all have an impact on your brain’s health.

Instead of entrusting the health of your brain to a so-called wonder ingredient initially found in jellyfish, I recommend focusing on improving lifestyle factors that can contribute to Optimal brain functioning.

These are some of them:

  • Regularly engaging in physical activity.
  • Getting a good night’s sleep of 7-8 hours.
  • Breathwork and contemplative techniques may help you become more conscious.
  • Keeping mind-altering chemicals such as alcohol and narcotics out of your system.
  • Limiting sugar, processed carbs, and harmful fats while eating a balanced diet rich in fruits, vegetables, whole grains, and wild-caught seafood.
  • Consult your doctor about vitamin D and omega-3 fatty acid supplements, which may help reduce inflammation, which leads to illness and cognitive loss.
  • Puzzles, reading, and learning a new language are all brain-healthy hobbies.

The “truth about prevagen” is a review of the ingredients, side effects, cost, and more for this supplement.

Frequently Asked Questions

What are the negative side effects of Prevagen?

A: The negative side effects of Prevagen are the following: headaches, nausea, dizziness and itchy skin.

What is the cost of Prevagen medication?

A: Prevagen is a dietary supplement that helps to protect the bodys neurons, which are cells in your brain that process and transmit information. A bottle of Prevagen will cost $49 on Amazon.

What is the main active ingredient in Prevagen?

A: The main active ingredient in Prevagen is a substance called alpha-GPC, which is short for gamma-phenylacetylglutamine. This compound can improve cognitive function and memory in older adults who already have mild dementia or Alzheimers disease by increasing the brain’s levels of acetylcholine, thereby improving both short term and long term memory.

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Prevagen Review: Ingredients, Side Effects, Cost, and More (2024)


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